Cancer Radiation

Posts Tagged ‘study’

Patients with stage III colon cancer treated with 5-FU-based chemotherapy after complete surgical removal of their tumor after 1995 had improved overall survival with no change in time to recurrence compared to patients treated before 1995. In contrast, patients with stage II colon cancer treated after 1995 had longer time to recurrence and time from recurrence to death compared to those patients treated prior to 1995, according to Mayo Clinic and Gr Hospitalier Pitie-Salpetriere, Paris, researchers. They will present the study’s findings on June 4-8, 2010, at the American Society of Clinical Oncology annual meeting in Chicago. “By combining information from 21 cancer treatment trials for patients with stage II and stage III colon cancer, our analysis determined that those patients treated after 1995 had improved overall survival,” says Dan Sargent, Ph.D., Mayo Clinic biostatistician, North Central Cancer Treatment Group statistician and senior author on the study. The analysis compared patient data from more than 18000 patients with stage II and stage III colon cancer treated with 5-FU-based chemotherapy after their primary tumor had been surgically removed for the time period 1978-1995 versus 1996-2007.

The results of a large randomized study have been re-analyzed with new findings. Find out the results and their significance.

Product Description
Thoracic tumor moving due to respiration is the challenge in radiotherpay today. Four-dimensional (4D) radiation treatmen planning was proposed to solve the tumor with motion problem. In this book, we applied the deformable image registration, called optical flow method (OFM), to deal with integral radiation dose through time as dose mapping. Validations of a dose mapping program using OFM, and to demonstrate application of the programin radiotherapy follow-up evaluation were discussed detail in book. For the purpose of validation, the deformation matrices between 4D CT data of different simulated respiration phases of a phantomwere calculated using OFM. The matrices were then used to map doses of all phases to a single-phase image, and summed in equal time weighting. Besides, several clinical cases with proposed method were all pesented in this book, too.

4D Study of Thoracic Cancer Radiation Treatment: 4-dimension radiotherapy and radiation treatment planning in thoracic section