Posts Tagged ‘Drug’

Physicians’ Cancer Chemotherapy Drug Manual

Product Description
Completely revised and updated for 2010, the Physicians Cancer Chemotherapy Drug Manual is an up-to-date guide with the latest information on standard therapy and recent advances in chemotherapy. Written by world-class experts in the clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens both on-and off-label for the treatment of all major cancers.

Physicians’ Cancer Chemotherapy Drug Manual

Clinically Relevant Resistance in Cancer Chemotherapy

Product Description
The introduction of new anticancer drugs and drug combinations, as well as the use of high-dose chemotherapy with growth factor and hemopoietic stem cell support, has greatly increased clinical remission rates. Unfortunately palliation, rather than cure, remains the most realistic goal of chemotherapy for many patients. The failure to cure metastatic cancer is commonly attributed to drug “resistance”. Resistance can be broadly viewed as the survival of malignant cells because of a failure to deliver an effective drug dose to the (cellular) target, resulting from any one of or combination of individual factors. For example, inter-individual genetic differences in drug metabolism, as well as differences in tumor kinetics and vascularization, may be important for treatment outcome. In addition, numerous molecular mechanisms of resistance have been elucidated at the level of the individual tumor cell. The present volume reviews clinically relevant aspects of the pharmacokinetics of commonly used anticancer agents as well as mechanisms of cellular/experimental resistance to such agents. This extends to technological advances that enable high-throughput studies of genetic polymorphisms, which has opened up new avenues to the study of drug resistance and to the individualization of chemotherapy in order to decrease clinical toxicity and optimize treatment results.

“This text provides a comprehensive review of the mechanisms of resistance to cancer chemotherapuetic agents. Leading experts discuss molecular and biochemical pathways that influence cytotoxicity. Knowledge of these potential obstacles to therapy will allow for the development of more effective strategies to treat malignant diseases.”

Steven T. Rosen, M.D., Series Editor

Clinically Relevant Resistance in Cancer Chemotherapy

Clinically Relevant Resistance in Cancer Chemotherapy

Product Description
The introduction of new anticancer drugs and drug combinations, as well as the use of high-dose chemotherapy with growth factor and hemopoietic stem cell support, has greatly increased clinical remission rates. Unfortunately palliation, rather than cure, remains the most realistic goal of chemotherapy for many patients. The failure to cure metastatic cancer is commonly attributed to drug “resistance”. Resistance can be broadly viewed as the survival of malignant cells because of a failure to deliver an effective drug dose to the (cellular) target, resulting from any one of or combination of individual factors. For example, inter-individual genetic differences in drug metabolism, as well as differences in tumor kinetics and vascularization, may be important for treatment outcome. In addition, numerous molecular mechanisms of resistance have been elucidated at the level of the individual tumor cell. The present volume reviews clinically relevant aspects of the pharmacokinetics of commonly used anticancer agents as well as mechanisms of cellular/experimental resistance to such agents. This extends to technological advances that enable high-throughput studies of genetic polymorphisms, which has opened up new avenues to the study of drug resistance and to the individualization of chemotherapy in order to decrease clinical toxicity and optimize treatment results.

“This text provides a comprehensive review of the mechanisms of resistance to cancer chemotherapuetic agents. Leading experts discuss molecular and biochemical pathways that influence cytotoxicity. Knowledge of these potential obstacles to therapy will allow for the development of more effective strategies to treat malignant diseases.”

Steven T. Rosen, M.D., Series Editor

Clinically Relevant Resistance in Cancer Chemotherapy

Clinically Relevant Resistance in Cancer Chemotherapy

Product Description
The introduction of new anticancer drugs and drug combinations, as well as the use of high-dose chemotherapy with growth factor and hemopoietic stem cell support, has greatly increased clinical remission rates. Unfortunately palliation, rather than cure, remains the most realistic goal of chemotherapy for many patients. The failure to cure metastatic cancer is commonly attributed to drug “resistance”. Resistance can be broadly viewed as the survival of malignant cells because of a failure to deliver an effective drug dose to the (cellular) target, resulting from any one of or combination of individual factors. For example, inter-individual genetic differences in drug metabolism, as well as differences in tumor kinetics and vascularization, may be important for treatment outcome. In addition, numerous molecular mechanisms of resistance have been elucidated at the level of the individual tumor cell. The present volume reviews clinically relevant aspects of the pharmacokinetics of commonly used anticancer agents as well as mechanisms of cellular/experimental resistance to such agents. This extends to technological advances that enable high-throughput studies of genetic polymorphisms, which has opened up new avenues to the study of drug resistance and to the individualization of chemotherapy in order to decrease clinical toxicity and optimize treatment results.

“This text provides a comprehensive review of the mechanisms of resistance to cancer chemotherapuetic agents. Leading experts discuss molecular and biochemical pathways that influence cytotoxicity. Knowledge of these potential obstacles to therapy will allow for the development of more effective strategies to treat malignant diseases.”

Steven T. Rosen, M.D., Series Editor

Clinically Relevant Resistance in Cancer Chemotherapy

Physicians’ Cancer Chemotherapy Drug Manual

Product Description
Completely revised and updated for 2010, the Physicians Cancer Chemotherapy Drug Manual is an up-to-date guide with the latest information on standard therapy and recent advances in chemotherapy. Written by world-class experts in the clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens both on-and off-label for the treatment of all major cancers.

Physicians’ Cancer Chemotherapy Drug Manual

Physicians’ Cancer Chemotherapy Drug Manual

Product Description
Completely revised and updated for 2010, the Physicians Cancer Chemotherapy Drug Manual is an up-to-date guide with the latest information on standard therapy and recent advances in chemotherapy. Written by world-class experts in the clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens both on-and off-label for the treatment of all major cancers.

Physicians’ Cancer Chemotherapy Drug Manual

Physicians’ Cancer Chemotherapy Drug Manual

Product Description
Completely revised and updated for 2010, the Physicians Cancer Chemotherapy Drug Manual is an up-to-date guide with the latest information on standard therapy and recent advances in chemotherapy. Written by world-class experts in the clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens both on-and off-label for the treatment of all major cancers.

Physicians’ Cancer Chemotherapy Drug Manual

Physicians’ Cancer Chemotherapy Drug Manual 2004: Spiral

Product Description
Completely revised and updated for 2004, this practical handbook is an up-to-date guide to all aspects of cancer chemotherapy. The book provides a comprehensive, easy to use catalogue of over 100 drugs –both on- and off-label– commonly used in cancer treatment. All entries have been updated meticulously as necessary, and this new edition includes five new agents (recently or about to be FDA approved). A section on Common Chemotherapy Regimens provides a quick reference to management of specific cancers, arranged alphabetically. An introductory chapter on Principles of Chemotherapy offers a concise update and overview of the field.

Physicians’ Cancer Chemotherapy Drug Manual 2004: Spiral

Physicians’ Cancer Chemotherapy Drug Manual

Product Description
Completely revised and updated for 2010, the Physicians Cancer Chemotherapy Drug Manual is an up-to-date guide with the latest information on standard therapy and recent advances in chemotherapy. Written by world-class experts in the clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens both on-and off-label for the treatment of all major cancers.

Physicians’ Cancer Chemotherapy Drug Manual

With Pancreatic Cancer using Gemzar as the chemo. What chemo drug is used with radiation?

I know that Gemzar will not be used, what is the drug of choice with chemo and radiation for pancreatic cancer